ClassID:

108937

C12N9/22 - page 19 - CPC Classification

Classification description:

Enzymes; Proenzymes; Compositions thereof ; Processes for preparing, activating, inhibiting, separating or purifying enzymes; Hydrolases (3) acting on ester bonds (3.1) Ribonucleases RNAses, DNAses

Recent Application in this class:
#5401
20190241880
2019-08-08

Proximity-dependent biotinylation and uses thereof

#5402
20190241879
2019-08-08

METHODS AND COMPOUNDS FOR GENE INSERTION INTO REPEATED CHROMOSOME REGIONS FOR MULTI-LOCUS ASSORTMENT AND DAISYFIELD DRIVES

#5403
20190241878
2019-08-08

OPTIMIZED BINUCLEASE FUSIONS AND METHODS

#5404
20190241877
2019-08-08

Engineered target specific nucleases

#5405
20190241876
2019-08-08

Delivery of cargo proteins via ARRDC1-mediated microvesicles (ARMMs)

#5406
20190240595
2019-08-08

Use of electrochemical devices or systems comprising redox-functionalized electrodes for bioseparation and biocatalysis

#5407
20190233847
2019-08-01

Variant RNA-guided polypeptides and methods of use

#5408
20190233846
2019-08-01

Methods of enhancing chromosomal homologous recombination

#5409
20190233843
2019-08-01

TRANSPOSON SYSTEM AND METHODS OF USE

#5410
20190233835
2019-08-01

Cell-permeable (CP)-Cas9 recombinant protein and uses thereof

#5411
20190233820
2019-08-01

NANOPARTICLES FUNCTIONALIZED WITH GENE EDITING TOOLS AND RELATED METHODS

#5412
20190233816
2019-08-01

STRUCTURE-GUIDED CHEMICAL MODIFICATION OF GUIDE RNA AND ITS APPLICATIONS

#5413
20190233814
2019-08-01

CRISPR enzymes and systems

#5414
20190233806
2019-08-01

CONDITIONAL ACTIVATION OF NUCLEIC ACID-GUIDED ENDONUCLEASES

#5415
20190233805
2019-08-01

TARGETABLE PROTEINS FOR EPIGENETIC MODIFICATION AND METHODS FOR USE THEREOF

#5416
20190231808
2019-08-01

Compositions and methods for the treatment of expanded repeat-associated disorders

#5417
20190226024
2019-07-25

Method of determining target nucleic acid

#5418
20190225991
2019-07-25

Methods and compositions for genome editing in non-dividing cells

#5419
20190225990
2019-07-25

Methods, compositions and kits for increasing genome editing efficiency

#5420
20190225989
2019-07-25

GENE KNOCKIN METHOD AND KIT FOR GENE KNOCKIN

#5421
20190225988
2019-07-25

Genomic integration of DNA fragments in fungal host cells

#5422
20190225974
2019-07-25

TARGETED GENOME OPTIMIZATION IN PLANTS

#5423
20190225963
2019-07-25

Excision of retroviral nucleic acid sequences

#5424
20190225961
2019-07-25

Compositions and methods relating to synthetic RNA polynucleotides created from synthetic DNA oligonucleotides

#5425
20190225956
2019-07-25

LENTIVIRAL DELIVERY OF CRISPR/CAS CONSTRUCTS THAT CLEAVE GENES ESSENTIAL FOR HIV-1 INFECTION AND REPLICATION

#5426
20190225955
2019-07-25

Evolved Cas9 proteins for gene editing

#5427
20190224340
2019-07-25

Materials and methods for treatment of pain related disorders

#5428
20190224246
2019-07-25

Method for the treatment of lysosomal storage diseases

#5429
20190218611
2019-07-18

METHODS FOR VARIANT DETECTION

#5430
20190218602
2019-07-18

CRISPR enzymes and systems

#5431
20190218560
2019-07-18

Methods and compositions for regulation of transgene expression

#5432
20190218548
2019-07-18

Method for producing N-acetylglucosamine by co-utilizing glucose and xylose based on CRISPRi

#5433
20190218547
2019-07-18

Structure-engineered guide RNA

#5434
20190218533
2019-07-18

Genome-Scale Engineering of Cells with Single Nucleotide Precision

#5435
20190218532
2019-07-18

Streptococcus Canis Cas9 as a Genome Engineering Platform with Novel PAM Specificity

#5436
20190218261
2019-07-18

TARGETED ENHANCED DNA DEMETHYLATION

#5437
20190218257
2019-07-18

NOVEL NUCLEOSIDE TRIPHOSPHATE TRANSPORTER AND USES THEREOF

#5438
20190216950
2019-07-18

Gene editing-based method of attenuating the beta-amyloid pathway

#5439
20190216938
2019-07-18

Derivatisation of Insulin with Polysaccharides

#5440
20190216064
2019-07-18

Cytoplasmic incompatibility factors and methods for controlling anthropods

#5441
20190216063
2019-07-18

Genetically Edited Animal

#5442
20190211362
2019-07-11

Materials and methods for treatment of myotonic dystrophy type 1 (DM1) and other related disorders

#5443
20190211353
2019-07-11

Means and methods to induce apomixis in plants

#5444
20190211317
2019-07-11

PEPTIDES AND NANOPARTICLES FOR INTRACELLULAR DELIVERY OF GENOME-EDITING MOLECULES

#5445
20190211312
2019-07-11

Compositions of and methods for in vitro viral genome engineering

#5446
20190211284
2019-07-11

Polypeptide variants

#5447
20190207890
2019-07-04

RNA targeting methods and compositions

#5448
20190203259
2019-07-04

Method of monitoring RNase L activity

#5449
20190203231
2019-07-04

Methods for treating cells containing fusion genes

#5450
20190203207
2019-07-04

Anabolic Enhancers for Ameliorating Neurodegeneration

#5451
20190203198
2019-07-04

Method for converting genome sequence of gram-positive bacterium by specifically converting nucleic acid base of targeted DNA sequence, and molecular complex used in same

#5452
20190202856
2019-07-04

ENGINEERED CRISPR PROTEINS FOR COVALENT TAGGING NUCLEIC ACIDS

#5453
20190201501
2019-07-04

COMPOSITIONS AND METHODS FOR CELL TARGETED HPV TREATMENT

#5454
20190195894
2019-06-27

Microbial-based biosensors

#5455
20190194729
2019-06-27

RECOGNITION SEQUENCES FOR I-CREI-DERIVED MEGANUCLEASES AND USES THEREOF

#5456
20190194693
2019-06-27

CRISPR enabled multiplexed genome engineering

#5457
20190194692
2019-06-27

CRISPR-CAS system for a filamentous fungal host cell

#5458
20190194691
2019-06-27

Vector-free delivery of gene editing proteins and compositions to cells and tissues

#5459
20190194653
2019-06-27

CRISP-seq, an integrated method for massively parallel single cell RNA-seq and CRISPR pooled screens

#5460
20190194652
2019-06-27

HIV CLINICAL PLAN

#5461
20190194633
2019-06-27

COMPOSITIONS, SYSTEMS AND METHODS FOR PROGRAMMING IMMUNE CELL FUNCTION THROUGH TARGETED GENE REGULATION

#5462
20190194632
2019-06-27

Methods and compositions for genomic editing

#5463
20190192691
2019-06-27

Regulated biocircuit systems

#5464
20190185883
2019-06-20

CAS9 proteins including ligand-dependent inteins

#5465
20190185882
2019-06-20

Compositions and Methods of Delivering Treatments for Latent Viral Infections

#5466
20190185880
2019-06-20

TRANSPOSON SYSTEM AND METHODS OF USE

#5467
20190185860
2019-06-20

Manipulated immunoregulatory element and immunity altered thereby

#5468
20190185850
2019-06-20

SINGLE GUIDE RNA/CRISPR/CAS9 SYSTEMS, AND METHODS OF USE THEREOF

#5469
20190185849
2019-06-20

COMPOSITIONS AND METHODS FOR GENE EDITING

#5470
20190185848
2019-06-20

Means and methods for modifying multiple alleles

#5471
20190185847
2019-06-20

Improving a Microorganism by CRISPR-Inhibition

#5472
20190185846
2019-06-20

Automated cell processing methods, modules, instruments, and systems

#5473
20190185844
2019-06-20

Tuning CRISPR/Cas9 activity with chemically modified nucleotide substitutions

#5474
20190185832
2019-06-20

DIET CONTROLLED EXPRESSION OF A NUCLEIC ACID ENCODING CAS9 NUCLEASE AND USES THEREOF

#5475
20190185831
2019-06-20

CRISPR-associated (CAS) protein

#5476
20190185819
2019-06-20

Human induced pluripotent stem cells for high efficiency genetic engineering

#5477
20190177751
2019-06-13

Production of itaconic acid

#5478
20190177722
2019-06-13

Compositions and methods of modifying a plant genome to produce a MS9, MS22, MS26, or MS45 male-sterile plant

#5479
20190177720
2019-06-13

Frequency-based modulation of diverse species in a nucleic acid library

#5480
20190177710
2019-06-13

Method For Screening Target Specific Nuclease Using Multi-Target System Of On-Target And Off-Target And Use Thereof

#5481
20190177709
2019-06-13

Regulation of gene expression using engineered nucleases

#5482
20190177421
2019-06-13

CHIMERIC ANTIGEN RECEPTORS AND METHODS FOR USE

#5483
20190177374
2019-06-13

Methods of transcription activator like effector assembly

#5484
20190169653
2019-06-06

METHOD FOR PREPARING GENE KNOCK-IN CELLS

#5485
20190169652
2019-06-06

Compositions and methods for treating CEP290 associated disease

#5486
20190169651
2019-06-06

Using programmable DNA binding proteins to enhance targeted genome modification

#5487
20190169650
2019-06-06

Using programmable DNA binding proteins to enhance targeted genome modification

#5488
20190169649
2019-06-06

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

#5489
20190169648
2019-06-06

METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION

#5490
20190169647
2019-06-06

METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION

#5491
20190169646
2019-06-06

METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION

#5492
20190169645
2019-06-06

METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION

#5493
20190169644
2019-06-06

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

#5494
20190169643
2019-06-06

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

#5495
20190169642
2019-06-06

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

#5496
20190169641
2019-06-06

Methods and compositions or RNA-directed target DNA modification and for RNA-directed modulation of transcription

#5497
20190169640
2019-06-06

DNA-binding proteins and uses thereof

#5498
20190169639
2019-06-06

CRISPR-related methods and compositions with governing gRNAs

#5499
20190169620
2019-06-06

Treatment of HER2-Dependent Cancers by SORL1 Inhibition

#5500
20190169605
2019-06-06

Automated cell processing methods, modules, instruments, and systems

#5501
20190169604
2019-06-06

METHODS AND COMPOSITIONS RELATED TO BARCODE ASSISTED ANCESTRAL SPECIFIC EXPRESSION (BAASE)

#5502
20190169597
2019-06-06

GENOME EDITING ENHANCERS

#5503
20190169596
2019-06-06

Methods and compositions for genome editing via haploid induction

#5504
20190169595
2019-06-06

RNA targeting methods and compositions

#5505
20190169270
2019-06-06

COMPOSITIONS AND METHODS FOR INHIBITING ENDOGENOUS IMMUNOGLOBULIN GENES AND PRODUCING TRANSGENIC HUMAN IDIOTYPE ANTIBODIES

#5506
20190169240
2019-06-06

DNA-BINDING PROTEIN USING PPR MOTIF, AND USE THEREOF

#5507
20190167814
2019-06-06

Treatment And/Or Prevention Of DNA-Triplet Repeat Diseases Or Disorders

#5508
20190167768
2019-06-06

Compositions and methods for treating nonsteroidal anti-inflammatory drug (NSAID) associated coagulopathy, thrombocytopenia, glanzmann's thrombasthenia, and/or thrombosis

#5509
20190167720
2019-06-06

GENE EDITING FOR IMMUNOLOGICAL DESTRUCTION OF NEOPLASIA

#5510
20190161789
2019-05-30

Method for modifying target site in genome of eukaryotic cell, and method for detecting presence or absence of nucleic acid sequence to be detected at target site

#5511
20190161753
2019-05-30

Methods for cleaving DNA and RNA molecules

#5512
20190161752
2019-05-30

Enrichment of mutated cell free nucleic acids for cancer detection

#5513
20190161751
2019-05-30

Methods of screening using barcoded libraries

#5514
20190161743
2019-05-30

Self-Targeting Guide RNAs in CRISPR System

#5515
20190161742
2019-05-30

NOVEL CAS9 SYSTEMS AND METHODS OF USE

#5516
20190161707
2019-05-30

Cleaning compositions comprising enzymes

#5517
20190160186
2019-05-30

Materials and methods for treatment of friedreich ataxia and other related disorders

#5518
20190153530
2019-05-23

Method for detecting off-target sites of programmable nucleases in a genome

#5519
20190153477
2019-05-23

Materials and methods for treatment of pain related disorders

#5520
20190153476
2019-05-23

CRISPR-CAS SYSTEMS FOR ALTERING EXPRESSION OF GENE PRODUCTS

#5521
20190153451
2019-05-23

Methods for modulating insect hygro- and/or thermosensation

#5522
20190153441
2019-05-23

Materials and methods for treatment of autosomal dominant retinitis pigmentosa

#5523
20190153440
2019-05-23

MATERIALS AND METHODS FOR TREATMENT OF AUTOSOMAL DOMINANT RETINITIS PIGMENTOSA

#5524
20190153435
2019-05-23

Method for fragmenting DNA by nick translation

#5525
20190153430
2019-05-23

METHOD FOR GENOME EDITING

#5526
20190153429
2019-05-23

Methods and compositions for synthetic RNA endonucleases

#5527
20190153427
2019-05-23

DETERMINATION OF RNA IN BLOOD OR OTHER FLUIDS

#5528
20190153412
2019-05-23

Compositions and methods of use of CRISPR-Cas systems in nucleotide repeat disorders

#5529
20190151476
2019-05-23

Therapeutic applications of CPF1-based genome editing

#5530
20190151408
2019-05-23

COLICINS FOR TREATING BACTERIAL INFECTIONS

#5531
20190144929
2019-05-16

Devices for CRISPR effector system based diagnostics

#5532
20190144920
2019-05-16

Compositions and methods for targeted depletion, enrichment, and partitioning of nucleic acids using CRISPR/Cas system proteins

#5533
20190144888
2019-05-16

CRISPR/Cas9 complex for genomic editing

#5534
20190144867
2019-05-16

METHOD FOR MITIGATING METASTASIS

#5535
20190144853
2019-05-16

Targeted in situ protein diversification by site directed DNA cleavage and repair

#5536
20190144840
2019-05-16

Methods for treating or preventing HBV infection or HBV related diseases

#5537
20190144489
2019-05-16

Methods and compositions for nucleoside triphosphate and ribonucleic acid production

#5538
20190142973
2019-05-16

Engineered nucleases useful for treatment of hemophilia A

#5539
20190141968
2019-05-16

Recombinant adeno-associated viruses for delivering gene editing molecules to embryonic cells

#5540
20190136264
2019-05-09

Particles coated with catalysts useful for splicing nucleic acids

#5541
20190136261
2019-05-09

Genetic modification of cytokine inducible SH2-containing protein (CISH) gene

#5542
20190136253
2019-05-09

Application of gene in improving photosynthesis of rice

#5543
20190136248
2019-05-09

NOVEL GUIDE RNA/CAS ENDONUCLEASE SYSTEMS

#5544
20190136231
2019-05-09

LIPID NANOPARTICLE FORMULATIONS FOR CRISPR/CAS COMPONENTS

#5545
20190136230
2019-05-09

GENETICALLY ENGINEERED CELLS AND METHODS OF MAKING THE SAME

#5546
20190136212
2019-05-09

Combination chemotherapy for the treatment of cancer

#5547
20190136211
2019-05-09

Method For In Vivo High-Throughput Evaluating Of RNA-Guided Nuclease Activity

#5548
20190136210
2019-05-09

Cas9 fusion molecules, gene editing systems, and methods of use thereof

#5549
20190134221
2019-05-09

CRISPR/CAS-RELATED METHODS AND COMPOSITIONS FOR TREATING DUCHENNE MUSCULAR DYSTROPHY

#5550
20190127762
2019-05-02

Methods for increasing efficiency of nuclease-mediated gene editing in stem cells

#5551
20190127713
2019-05-02

CRISPR/CAS9-BASED REPRESSORS FOR SILENCING GENE TARGETS IN VIVO AND METHODS OF USE

#5552
20190127665
2019-05-02

Detergent compositions comprising polypeptide variants

#5553
20190127664
2019-05-02

Detergent compositions comprising polypeptide variants

#5554
20190126293
2019-05-02

Method of dewatering post fermentation fluids

#5555
20190125798
2019-05-02

Chimeric antigen receptor (CAR) and T cell receptor (TCR) modified T cells

#5556
20190119701
2019-04-25

METHODS FOR IMPROVED HOMOLOGOUS RECOMBINATION AND COMPOSITIONS THEREOF

#5557
20190119660
2019-04-25

Therapeutic nuclease compositions and methods

#5558
20190119638
2019-04-25

Transgenic T cell and chimeric antigen receptor T cell compositions and related methods

#5559
20190119337
2019-04-25

Methods of treating mitochondrial disorders

#5560
20190112643
2019-04-18

Immobilized RNPs for sequence-specific nucleic acid capture and digital detection

#5561
20190112636
2019-04-18

METHODS AND COMPOSITIONS FOR NUCLEIC ACID DETECTION

#5562
20190112619
2019-04-18

Methods and compositions for the targeted modification of a mouse ES cell genome

#5563
20190112614
2019-04-18

EXCISION OF TRANSGENES IN GENETICALLY MODIFIED ORGANISMS

#5564
20190112592
2019-04-18

SITE-SPECIFIC NUCLEASE SINGLE-CELL ASSAY TARGETING GENE REGULATORY ELEMENTS TO SILENCE GENE EXPRESSION

#5565
20190112587
2019-04-18

Engineered nucleic-acid targeting nucleic acids

#5566
20190112586
2019-04-18

Engineered Nucleases and Their Uses for Nucleic Acid Assembly

#5567
20190111153
2019-04-18

Compositions and methods to program therapeutic cells using targeted nucleic acid nanocarriers

#5568
20190106715
2019-04-11

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

#5569
20190106714
2019-04-11

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

#5570
20190106713
2019-04-11

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

#5571
20190106712
2019-04-11

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

#5572
20190106711
2019-04-11

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

#5573
20190106710
2019-04-11

Oncogenic Models Based on Delivery and Use of the CRISPR-Cas Systems, Vectors and Compositions

#5574
20190106693
2019-04-11

Methods of making and using guide RNA for use with Cas9 systems

#5575
20190106688
2019-04-11

FUSION PROTEIN FOR CRISPR/CAS SYSTEM AND COMPLEX COMPRISING THE SAME AND USES THEREOF

#5576
20190106687
2019-04-11

Engineered CRISPR-Cas9 nucleases with altered PAM specificity

#5577
20190100784
2019-04-04

RNA analysis by total hydrolysis and quantification of released nucleosides

#5578
20190100775
2019-04-04

Engineered nucleic acid-targeting nucleic acids

#5579
20190100762
2019-04-04

NOVEL CAS9 SYSTEMS AND METHODS OF USE

#5580
20190100745
2019-04-04

NOVEL CAS SYSTEMS AND METHODS OF USE

#5581
20190100737
2019-04-04

Peptide-mediated delivery of RNA-guided endonuclease into cells

#5582
20190100736
2019-04-04

Method for using heat-resistant mismatch endonuclease

#5583
20190100732
2019-04-04

ASSAY FOR THE REMOVAL OF METHYL-CYTOSINE RESIDUES FROM DNA

#5584
20190099381
2019-04-04

Nanocapsule delivery system for ribonucleoproteins

#5585
20190093129
2019-03-28

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

#5586
20190093128
2019-03-28

METHODS FOR GENOME EDITING IN ZYGOTES

#5587
20190093125
2019-03-28

HIGH EFFICIENCY, HIGH THROUGHPUT GENERATION OF GENETICALLY MODIFIED NON-HUMAN MAMMALS BY MULTI-CYCLE ELECTROPORATION OF CAS9 PROTEIN

#5588
20190093117
2019-03-28

METHODS AND COMPOSITIONS FOR VIRAL-BASED GENE EDITING IN PLANTS

#5589
20190093114
2019-03-28

Fungal genome modification systems and methods of use

#5590
20190093107
2019-03-28

Crispr enzymes and systems

#5591
20190093104
2019-03-28

Coexpression of CAS9 and TREX2 for targeted mutagenesis

#5592
20190093099
2019-03-28

Adenosine nucleobase editors and uses thereof

#5593
20190093092
2019-03-28

RNA GUIDED ERADICATION OF VARICELLA ZOSTER VIRUS

#5594
20190093091
2019-03-28

COMPOSITIONS FOR ERADICATING FLAVIVIRUS INFECTIONS IN SUBJECTS

#5595
20190093090
2019-03-28

CRISPR-associated transposases and uses thereof

#5596
20190085356
2019-03-21

System for site-specific modification of ALS gene using CRISPR-Cas9 system for production of herbicide-resistant rice and use of same

#5597
20190085342
2019-03-21

Method for converting monocot plant genome sequence in which nucleic acid base in targeted DNA sequence is specifically converted, and molecular complex used therein

#5598
20190085329
2019-03-21

RNA-directed DNA cleavage by the Cas9-crRNA complex

#5599
20190085326
2019-03-21

Negative feedback regulation of HIV-1 by gene editing strategy

#5600
20190085325
2019-03-21

Conditional CRISPR sgRNA expression

#5601
20190085324
2019-03-21

Assays for massively combinatorial perturbation profiling and cellular circuit reconstruction

#5602
20190085308
2019-03-21

Methods of generating nucleic acid fragments

#5603
20190085307
2019-03-21

Method for using heat-resistant mismatch endonuclease

#5604
20190085288
2019-03-21

Methods for the treatment of corneal dystrophies

#5605
20190078099
2019-03-14

CELL LINE FOR RECOMBINANT PROTEIN AND/OR VIRAL VECTOR PRODUCTION

#5606
20190071717
2019-03-07

CRISPR enzymes and systems

#5607
20190071688
2019-03-07

COMPOSITIONS AND METHODS FOR MODIFYING GENOMES

#5608
20190071673
2019-03-07

CRISPRs WITH IMPROVED SPECIFICITY

#5609
20190071657
2019-03-07

Engineered CRISPR-Cas9 nucleases

#5610
20190071656
2019-03-07

Transposase-mediated imaging of the accessible genome

#5611
20190070321
2019-03-07

Small molecules for dual function positron emission tomography (PET) and cell suicide switches

#5612
20190070314
2019-03-07

Nano/micromotors for active and dynamic intracellular payload delivery

#5613
20190062790
2019-02-28

METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION

#5614
20190062739
2019-02-28

Mitochondrial genome editing and regulation

#5615
20190062735
2019-02-28

CRISPR-CPF1-RELATED METHODS, COMPOSITIONS AND COMPONENTS FOR CANCER IMMUNOTHERAPY

#5616
20190062734
2019-02-28

GRNA FUSION MOLECULES, GENE EDITING SYSTEMS, AND METHODS OF USE THEREOF

#5617
20190062724
2019-02-28

RNA targeting methods and compositions

#5618
20190060482
2019-02-28

CATIONIC LIPID COMPOSITIONS FOR TISSUE-SPECIFIC DELIVERY

#5619
20190060364
2019-02-28

Intracellular genomic transplant and methods of therapy

#5620
20190060363
2019-02-28

Intracellular genomic transplant and methods of therapy

#5621
20190055583
2019-02-21

CRISPR mediated recording of cellular events

#5622
20190055552
2019-02-21

Compositions and methods for treating Huntington's disease and related disorders

#5623
20190055543
2019-02-21

Molecular cell diary system

#5624
20190055528
2019-02-21

Detergent composition comprising a DNase

#5625
20190055288
2019-02-21

Methods and products for genetic engineering

#5626
20190054192
2019-02-21

Isolation of extracellular vesicles (EVs) from red blood cells for gene therapy

#5627
20190054122
2019-02-21

Intracellular genomic transplant and methods of therapy

#5628
20190054111
2019-02-21

TALEN-based gene correction

#5629
20190048415
2019-02-14

DETECTION OF NUCLEIC ACIDS

#5630
20190048340
2019-02-14

NOVEL FAMILY OF RNA-PROGRAMMABLE ENDONUCLEASES AND THEIR USES IN GENOME EDITING AND OTHER APPLICATIONS

#5631
20190048338
2019-02-14

Structure-guided chemical modification of guide RNA and its applications

#5632
20190048337
2019-02-14

Crispr/Cas-Related Methods and Compositions for Treating Duchenne Muscular Dystrophy and Becker

#5633
20190048330
2019-02-14

Compositions and methods for regulating gene expression for targeted mutagenesis

#5634
20190046660
2019-02-14

Compositions and methods for genetically modifying myosin phosphatase target subunit (Mypt1) gene for lowering blood pressure

#5635
20190046579
2019-02-14

Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases

#5636
20190040416
2019-02-07

Cas discrimination using tuned guide RNA

#5637
20190040399
2019-02-07

CRISPR-CAS COMPONENT SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION

#5638
20190040397
2019-02-07

Method for producing DNA vectors from molecular bricks containing sequences of interest

#5639
20190040373
2019-02-07

Engineered nucleic-acid targeting nucleic acids

#5640
20190040372
2019-02-07

COMPOSITIONS AND METHODS COMPRISING SEQUENCES HAVING MEGANUCLEASE ACTIVITY

#5641
20190040371
2019-02-07

Mutant Cas9 proteins

#5642
20190040370
2019-02-07

TRACKING AND MANIPULATING CELLULAR RNA VIA NUCLEAR DELIVERY OF CRISPR/CAS9

#5643
20190038780
2019-02-07

VECTORS AND SYSTEM FOR MODULATING GENE EXPRESSION

#5644
20190038724
2019-02-07

Adeno-Associated Virus-Mediated CRISPR-Cas9 Treatment of Ocular Disease

#5645
20190032158
2019-01-31

Methods and compositions for targeted single-stranded cleavage and targeted integration

#5646
20190032156
2019-01-31

METHODS AND COMPOSITIONS FOR ASSESSING CRISPR/CAS-INDUCED RECOMBINATION WITH AN EXOGENOUS DONOR NUCLEIC ACID IN VIVO

#5647
20190032155
2019-01-31

Cas-ready mouse embryonic stem cells and mice and uses thereof

#5648
20190032131
2019-01-31

GENOME EDITING DETECTION

#5649
20190032091
2019-01-31

Nuclease-mediated genome editing of primary cells and enrichment thereof

#5650
20190032090
2019-01-31

Compositions and Methods to Treat Latent Viral Infections

#5651
20190032089
2019-01-31

CRISPR/Cas9 complex for introducing a functional polypeptide into cells of blood cell lineage

#5652
20190032088
2019-01-31

MICELLE BASED SYSTEM NUCLEASE ENCAPSULATION FOR IN-VIVO GENE EDITING

#5653
20190032057
2019-01-31

METHODS AND COMPOSITIONS FOR RNA-GUIDED TREATMENT OF HIV INFECTION

#5654
20190032052
2019-01-31

METHODS, SYSTEMS, AND APPARATUS FOR IDENTIFYING TARGET SEQUENCES FOR CAS ENZYMES OR CRISPR-CAS SYSTEMS FOR TARGET SEQUENCES AND CONVEYING RESULTS THEREOF

#5655
20190032049
2019-01-31

Permanent epigenetic gene silencing

#5656
20190032036
2019-01-31

Crispr enzyme mutations reducing off-target effects

#5657
20190032035
2019-01-31

Mini-III RNases, Methods for Changing the Specificity of RNA Sequence Cleavage by Mini-III RNases, and Uses Thereof

#5658
20190032003
2019-01-31

Controlling metabolism by substrate cofeeding

#5659
20190030172
2019-01-31

Phosphonate-drug conjugates

#5660
20190024123
2019-01-24

Genome Editing In Bacillus Host Cells

#5661
20190024098
2019-01-24

METHOD FOR MODIFYING GENOME SEQUENCE THAT SPECIFICALLY CONVERTS NUCLEOBASE OF TARGETED DNA SEQUENCE, AND MOLECULAR COMPLEX USED IN SAID METHOD

#5662
20190024086
2019-01-24

Methods and compositions for modulating gene expression

#5663
20190024079
2019-01-24

METHODS FOR EXTENDING THE REPLICATIVE CAPACITY OF SOMATIC CELLS DURING AN EX VIVO CULTIVATION PROCESS

#5664
20190024073
2019-01-24

EDITING MITOCHONDRIAL DNA

#5665
20190024070
2019-01-24

REWIRING ABERRANT CANCER SIGNALING TO A THERAPEUTIC EFFECTOR RESPONSE WITH A SYNTHETIC TWO-COMPONENT SYSTEM

#5666
20190024065
2019-01-24

PRIMARY HEMATOPOIETIC CELLS GENETICALLY ENGINEERED BY SLOW RELEASE OF NUCLEIC ACIDS USING NANOPARTICLES

#5667
20190022192
2019-01-24

Gene editing of deep intronic mutations

#5668
20190017075
2019-01-17

ENGINEERED MEGANUCLEASES WITH RECOGNITION SEQUENCES FOUND IN THE HUMAN BETA-2 MICROGLOBULIN GENE

#5669
20190017058
2019-01-17

CRISPR-CAS COMPONENT SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION

#5670
20190017055
2019-01-17

Real-time reporter systems for monitoring base editing

#5671
20190017045
2019-01-17

METHODS AND COMPOSITION FOR THE PRODUCTION OF SEQUENCE SPECIFIC ANTIMICROBIALS

#5672
20190017042
2019-01-17

Using nucleosome interacting protein domains to enhance targeted genome modification

#5673
20190017037
2019-01-17

Method for using heat-resistant mismatch endonuclease

#5674
20190014757
2019-01-17

Method for producing an animal comprising a germline genetic modification

#5675
20190010520
2019-01-10

METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION

#5676
20190010519
2019-01-10

Compositions and methods for enhanced genome editing

#5677
20190010518
2019-01-10

Compositions and Methods of Delivering Treatments for Latent Viral Infections

#5678
20190010496
2019-01-10

Genome editing for treating glioblastoma

#5679
20190010490
2019-01-10

Materials and methods for treatment of alpha-1 antitrypsin deficiency

#5680
20190010482
2019-01-10

Enzyme Composition for DNA End Repair, Adenylation, Phosphorylation

#5681
20190010481
2019-01-10

Variants of Cpf1 (Cas12a) with altered PAM specificity

#5682
20190010471
2019-01-10

Crispr enzyme mutations reducing off-target effects

#5683
20190010196
2019-01-10

Ubiquitin variants and uses therof as 53BP1 inhibitors

#5684
20190008985
2019-01-10

Nucleic acid products and methods of administration thereof

#5685
20190008899
2019-01-10

Tumor infiltrating lymphocytes and methods of therapy

#5686
20190002976
2019-01-03

Test for predicting the ability of a salmonid to utilise dietary pigment

#5687
20190002972
2019-01-03

Enzyme-pore constructs

#5688
20190002923
2019-01-03

METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION

#5689
20190002922
2019-01-03

METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION

#5690
20190002921
2019-01-03

METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION

#5691
20190002920
2019-01-03

METHODS AND KITS FOR CLONING-FREE GENOME EDITING

#5692
20190002889
2019-01-03

CRISPR RNA targeting enzymes and systems and uses thereof

#5693
20190002875
2019-01-03

CRISPR RNA targeting enzymes and systems and uses thereof

#5694
20190002868
2019-01-03

In vitro cleavage of DNA using argonaute

#5695
20190002826
2019-01-03

Method and composition for generating basal forebrain cholinergic neurons (BFCNS)

#5696
20190002824
2019-01-03

Nucleotide-specific recognition sequences for designer TAL effectors

#5697
20190002814
2019-01-03

Automated cell processing methods, modules, instruments, and systems

#5698
20190000997
2019-01-03

Nucleic acid products and methods of administration thereof

#5699
20190000996
2019-01-03

Nucleic acid products and methods of administration thereof

#5700
20190000995
2019-01-03

Nucleic acid products and methods of administration thereof